"Big News" is really No News in the embryonic stem cell industry...

That study, published in Circulation Journal in 2003, reported regenerated damaged heart tissue from ASCs gleaned from patients' own bone marrow. ["Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure." Perin EC, Dohmann HF, Borojevic R, et al. Circulation 2003 May 13;107(18):e9040-2]

Of that finding, Dr. Michael Rosen of Columbia University said, "This is the first approach where you have an opportunity to actually heal a heart."

(Ahem) The FIRST. Didn't see that plastered across the major media then, did we?

(Ahem Two) That's COLUMBIA UNIVERSITY, of NEW YORK CITY, the IVY LEAGUE university.

One real adult stem cell heart success not enough? How about 16 additional ones published in 18 respected medical journals including Journal of the American College of Cardiology, Journal Thoracic Cardiovascular Surgery, Circulation, Stem Cells and The Lancet?

ACUTE HEART DAMAGE

1. Joseph J et al., Safety and effectiveness of granulocyte-colony stimulating factor in mobilizing stem cells and improving cytokine profile in advanced chronic heart failure, American Journal of Cardiology 97, 681-684, 1 March 2006
   
2. Blocklet D et al., Myocardial homing of nonmobilized peripheral-blood CD34+ cells after intracoronary injection, Stem Cells 24, 333-336, February 2006
   
3. Janssens S et al., Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial, Lancet 367, 113-121, 14 January 2006
   
4. Patel AN et al., Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study, Journal Thoracic Cardiovascular Surgery 130, 1631-1638, December 2005, Updated: 4/11/2007
   
5. Ince H et al., Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI), Circulation 112, 3097-3106, 15 November 2005
   
6. Ince H et al., Prevention of left ventricular remodeling with granulocyte colony-stimulating after acute myocardial infarction, Circulation 112, I-73-I-80, 30 August 2005
   
7. Bartunek J et al., Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction, Circulation 112, I-178-I-183, 30 August 2005
   
8. Dohmann HFR et al., Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure, Circulation 112, 121-126, 26 July 2005
   
9. Wollert KC et al., "Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial", Lancet 364, 141-148, 10 July 2004
   
10. Britten MB et al., "Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction"; Circulation 108, 2212-2218; Nov 2003
    
11. Perin EC et al.; "Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure"; Circulation 107, r75-r83; published online May 2003
    
12. Stamm C et al.; "Autologous bone-marrow stem-cell transplantation for myocardial regeneration"; The Lancet 361, 45-46; 4 January 2003
    
13. Tse H-F et al.; "Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation"; The Lancet 361, 47-49; 4 January 2003
    
14. Strauer BE et al.; "Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans"; Circulation 106, 1913-1918; 8 October 2002
    
15. Strauer BE et al.; "Myocardial regeneration after intracoronary transplantation of human autologous stem cells following acute myocardial infarction"; Dtsch Med Wochenschr 126, 932-938; Aug 24, 2001
    
16. Menasche P et al. "Myoblast transplantation for heart failure." Lancet 357, 279-280; Jan 27, 2001
    
17. Menasche P et al. ["Autologous skeletal myoblast transplantation for cardiac insufficiency. First clinical case."] [article in French] Arch Mal Coeur Vaiss 94(3), 180-182; March 2001

    CHRONIC CORONARY ARTERY DISEASE
    

18. Strauer BE et al., Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease, Journal of the American College of Cardiology 46, 1651-1658, 1 November 2005

Cardiac stem cells (CSC) are indeed able to proliferate giving rise to other stem cells (property named self-renewal); they can differentiate into all the cells composing the cardiac tissue.

Cross-posted on Abortion Pundit